Recently I made the decision that acne just needs to be cured. So I started research in that vein, and I found that in 2001, scientists started work on an acne vaccine. More specifically, it is an anti-P.acnes bacteria vaccine. Since P. acnes is the bacteria implicated in acne formation and is a major culprit in acne development, if we can somehow turn off its genetic expression, the hope is that we can prevent or cure acne.
A brief history of the vaccine: A company called Corixa worked with a French company to decode the 2.8 milion base pairs that make up the P. acnes genome back in 2001. They then started working on identifying antigens in order to create a vaccine. Glaxo Smith Kline acquired Corixa in 2005. From there, mention of the vaccine seemed to fall off the map, until an article published in 2008 in the Journal of Investigative Dermatology surfaced. The article outlined research at the University of California San Diego in which scientists developed vaccines against P. acnes and successfully used the vaccine in both mice and in the lab using human sebum (skin oil) cells.
The trail seems to end there again. I’m in the process of contacting the researchers at UCSD to get more information. I find this area of work fascinating. I’ll keep you posted on anything I uncover. For now, let’s not get our hopes up too much however. Acne development is multi-faceted. While P. acnes plays a part, it is unknown how much it directly causes the other factors in acne development such as pores becoming clogged, oil overproduction, or inflammation.