Adapalene (Differin) Reviews

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Prescription summary (1,023 votes)

How well it works

:):):)
3.1/5
Agreeability

:):):)
3.4/5
Affordability

:):):)
3.4/5
Common brand names: Differin

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Elen, Utah, USA
Jun 29th, 2005
How well it works
:):):)
Agreeability
:):):)
Affordability
:):):)

I am 33 and experiencing acne for the first time in my life; I have always had the occasional pimple or two, but my face has become utterly blanketed with tiny hard bumps. These "pimples" are not generally inflamed (red or painful), but my skin feels like it is infested--it also feels like there might be some strange message written in braille... I am using adapalene in conjunction with clindamycin. After one month of religious use (and an initial period of irritated and dry skin), my acne totally cleared up. However, I woke up one morning to have it all back. Recently, I have decided to wash my face very very gently (I use a non-soap cream cleanser without a washcloth or any other abrasive material) morning and night and to use adapalene in the evenings and to use the clindamycin only in the mornings. I also use a moisturizing sunscreen every morning. After two weeks of the gentler approach, I've started seeing a reduction in my bumps and have some hope. I don't think adapalene is a wonder-drug by any means, but I think it can help. The key seems to be relaxing a little bit and avoiding the harsh cleansing measures that seem like a good idea when all you want to do is scrape your skin off in hopes that a totally fresh and clear layer will appear. I wish everyone the best in the quest for clear skin...

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Anonymous, FL
Jun 27th, 2005
How well it works
:):):)
Agreeability
:):):)
Affordability
:):)

differin works alright. i use it in combination with clindamycin lotion (it reduces the redness caused by differin) and doxyclyclin (pill). i guess differin works but it leaves my skin red and slightly flaky. i have had acne for years and so far differin has made it less active than before, but i still get breakouts. (by the way i am 16). by i did find out that pimples can be caused by shock to the skin. such as using extremely warm or cold water. (just a little piece of info). but i am a teenager so i guess pimples arent uncommon. i just use a cover up. (non oil based). good luck, i know it sucks to have oily skin.

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ALI, UK
Jun 27th, 2005
How well it works
:):):)
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:):):)
Affordability
:):):)

I suffered from teenage acne (16/17) and experienced excellent results with roaccutane. At 28 my acne returned (around chin area, few scattered spots on rest of face). Tried Differin gel for approx 18 months - used pea sized blob every night all over face. Used mild cleanser in the mornings. Blackheads reduced after a month or two and generally less inflamed blemishes. Skin a bit dry and flakey - corrected with oil-free moisturiser. Average product - good at keeping blackheads and spots reduced, but hasnt given me clear skin. Looking for new product as skin quite oily and still have spots coming up. Average product. Works 'OK' - better than over-the-counter cleansers etc.

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lex, MI
Jun 23rd, 2005
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:):)
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:):)

the derm. gave the gel to me about 2 years ago. im a teenager and i have bad acne on my back and face. the differen gel at first just dried up my face and made it break out more..so i just put it away and stopped using it. the derm. told me to too keep using it and it will eventually work. i started up again and my face broke out really bad and was really dry, the breakouts settled down in about 6weeks. but it still looked bad. finally it got better 2 weeks later and then it broke out again. my acne just seemed to keep coming and going. so now i gave up on it and i told my derm. i want something new. if i were you..dont waste your money and try something that works better...you dont want to go through what I went through. but thats just my opinion

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Charisse, Trinidad, West Indies
Jun 22nd, 2005
How well it works
:):)
Agreeability
:):):)
Affordability
:):):):):)

At 26 yrs. old I have never suffered with acne, not even as a teen, but coming off my birth control for one month certainly took care of that. Imagine how distressing this is for someone as vain as I am (just kidding, but I do take a lot of pride in my appearance, and this is shooting my self esteem to hell). I have been on Differin Cream for about two weeks now and have actually noticed an increase in my breakouts. I'm hoping this is the "must get worse before it gets better" stage that everyone keeps talking about. It makes my face somewhat dry and causes it to peel, which I guess helps eliminate some of the surface scarring and marks, but it means I have to moisturize every morning, which causes my skin to become oily later on in the day. No irritability and redness though, which I guess is good. In terms of affordability, my doc gave me free samples to use so I didn't have to pay a cent and I guess I wouldn't have lost anything if it proves not to work. However, I'm becoming slightly discouraged and am counting on my birth control to provide me with some form of relief if this cream does nothing. But I'll probably stick with it for the next couple of months in the hope that it will start working eventually. I must say, though, that reading the reviews on this website has been very depressing :)

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Anonymous, Highland Park, NJ
Jun 22nd, 2005
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I'm 28 and have had recurring acne all my life, but more recently I've become concerned with fine lines. My dermatologist prescribed differin (in CREAM formula) to rectify both the acne and fine lines. I had to wait out the initial two week TORTURE, where all the acne that you would have had for the next month or so comes to the surface all at once. But now it's been 3 weeks and my skin looks amazing! It is definitely flakier than before and I'm going to have to go out and buy moisturizer (a little nervous that this will cause me to break out again). But all in all, my skin looks 100 times better than before.

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Irene, Chicago
Jun 19th, 2005
How well it works
:)
Agreeability
:)
Affordability
:)

I have been using differin gel for 1 month. It does not work! My acne got worse then before and when I contacted my dermatologist all she kept saying was "give it a chance". She went as far as arguing with me about wanting to change my perscription. I had taken accutane 4 years ago and it worked 200% it was great!!!! I asked to be put back on and she totally disagreed what doctor does that? Well, I just wanted to share my story with those that have been convinced that they should try this very, very expensive cream. Please get a second opinion before trying "Differin" for your acne.

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Tianna-Alianna Rae, Syosset, NY
Jun 17th, 2005
How well it works
:)
Agreeability
:)
Affordability
:):):)

Differin was not effective at all. It did not reduce the number of pimples that I have up to now. I tried oral antibiotics and all but nothing works. I then tried Accutine but had to be placed in therapy because I was increasingly unstable mentally and often resorted to self-mutilation; a problem that is now cured but will always leave scars like my acne.

Right now I am not doing anything about my acne. I am still doing therapy for my mental health. But yes I have tried differin. It was so ineffective I slathered it on my scars from cutting and it actually faded them.

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Anna, Phili, PA
Jun 16th, 2005
How well it works
:):)
Agreeability
:):):):):)
Affordability
:):):):):)

I've been using this product (Differin) for a while now, along with another topical cream (Duac) and a pill. It has not been working for me. I hardly see a difference. I'm going to my dermotolagist tomorow to talk to him about how nothing has been working. Wish me luck!

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Dusta, NZ
Jun 15th, 2005
How well it works
:):):):)
Agreeability
:):):):)
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:)

Using it for about a month, in conjunction with cetaphil face wash & a topical solution on the spots in the AM. Got worse in one week but then things started clearing. I get like 1 spot at a time as opposed to 5 now, and they don't last as long. Not doing anything with blackheads tho. See what happens in a few more months.
I have oily T anyway so didn't really notice if this made it oilier. Started back swimming again a few times a week and it might be the chlorine in the water or something but it makes my face go quite dry (weird cos I don't have dry skin). So I recommend that for you oily people out there. Don't go overboard tho cos it will peel like anything.
And it cost $50 a tube here which is pretty hefty.
PS does anyone feel it is wrong to pop all this medication when you are generally healthy?? I was on doxycycline but I stopped after reading something about causing breast cancer with prolonged use and plus there's the whole superbugs thing.

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