Adapalene (Differin) Reviews

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Prescription summary (1,111 votes)

How well it works

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3.1/5
Agreeability

:):):)
3.3/5
Affordability

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3.4/5
Common brand names: Differin

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5 of 5 visitors found the following comment helpful.
rachel, south dakota
May 15th, 2006
How well it works
:):):):):)
Agreeability
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Affordability
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I suffered from moderate acne and was prescribed Differin gel about one year ago. After about a month of increased breakouts, it worked amazzzingly. The reason why you get the initial breakout is because the Differin IS working by eliminating the previously unSEEN lesions that would occur sooner or later. I think the month was well worth the wait. I rarely get any breakouts anymore; just when I'm premenstrual, so I take minocycline for a week or so. Differen did make my face red and dry at first, but now my face has much better tone than it ever has had before. Trust me, it is well worth the wait!

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3 of 3 visitors found the following comment helpful.
Anonymous
May 10th, 2006
How well it works
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If I could find the guy who came up with Differin...

I would give him a gigantic kiss! I "grew into" acne at age 18, and have tried dozens of treatments over the last six years. With other meds, my only results were vomiting, peeling, and a much lighter wallet.

I've been on Differin gel since last Monday (10 days) and my skin is 75% cleared up. I had the slightest bit of dryness, but Neutrogena moisturizer took care of that very quickly.

I can't wait to run into some old friends or go running around town. I've spent so many years crying, being upset, and feeling that my plague will never go away. The self-confidence that I've gained in less than two weeks is amazing.

My only regret is that I didn't get Differin gel sooner.

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1 of 1 visitors found the following comment helpful.
asldjlfjsf, alsdfalsjdf
May 8th, 2006
How well it works
:)
Agreeability
:)
Affordability
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I have been using Differin for almost 3 months now(along with Doxycycline), and haven't really seen a change in my skin. I'm still breaking out full force and have recently started devloping acne on my neck. I go back to the dermo in about 3 weeks and I'm requesting a stronger gel. I have had many friends use Differin and it has worked for them, but say that Differin is better in keeping acne away once it has already cleared.

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Valarindri, Portland, OR
May 7th, 2006
How well it works
:):):):)
Agreeability
:):):):)
Affordability
:):):):)

I have been dealing with moderate acne since I was 13 (now 22) and have tried at least a form of everything under the sun short of Accutane to "cure" my acne. My latest treatment after a year off of prescription medications has been Differin gel with Klaron lotion twice a day. I have been on this routine for 3 months now and after the intial breakout period (which was horrible for a month)has been very good. My normally dry, senstive has had almost no issues with the differin, and with a little of the Klaron in not dry in the least, which was a suprise and a big relief to me!! The Differin gel has worked wonders for most of my face and now I have just have a couple of problem spots to deal with, so keeping my fingers crossed that this will keep working for some time!! Overall, not perfect but very pleased!!

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Emerald, CA
May 7th, 2006
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:)
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I have been using Differin gel once a night along with Klaron in the morning and Minocycline pills twice daily. I've been taking them all together for 8 weeks now and no change at all. They said to give it 8-10 weeks, and I'm nearly there. I have an appointment to go back to the dermatologist to talk to her about it and see if I should switch to something else. :\

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Matt, Ljubljana,Slovenia
May 5th, 2006
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I've been using Differin for 2 months now and I satisfied with it. Had no side effects, but i've been using a slow approach to it; my dermatologist suggested that i start with just 2 applications per week for 2 weeks and slowly add 1 application every 2 weeks. I'm using it at night. No peeling,itching or scaling and acne that appeared lasted only 2-3 days and then disappeared and there were no flare-ups.I'm using the gel formulation and it's great-it's fast drying and non-greasy. Cream tends to be greasier because it's made for sensitive skin.
During the day i'm using SPF 30 moisturizer-can't be too careful!
I was also using azelaic acid and it worked fine too-smoothed out skin and cleared it. But Differin is also good for my post acne scars.

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Anne, Dallas, TX
May 3rd, 2006
How well it works
:):)
Agreeability
:)
Affordability
:):):)

I'm not very sure about differin. I have had it before, and it was after my experience with Retin A Micro, which got rid of my moderate acne as well as a layer of epithelial layer of skin. I was so red and my face was peeling so badly that you could have easily mistaken me for a stop light. The first time, differin helped to keep acne away after I got rid of it.

This time though, I'm not very sure. I've been on it for a month. I do know that it worsens the acne for the first three weeks. But what's strange is that it would appear to be getting better only to wake up the next day and the acne come back full blown. Also it's making my forehead (where I apply differin since that's where my acne is the most severe) very oily and shiny even after washing my face lightly in the morning from the night before's application. It itches too. I also got the cream instead of the gel and am wondering if that's why I'm having the negative effects.

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2 of 2 visitors found the following comment helpful.
John, NEW JERSEY
Apr 30th, 2006
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I use this along with Duac! It's great! Two weeks so far and clear up all fast! Get it along with Differin! Read my ratings for Duac! and you'll know a lot of info! What funny people complain its a 100 bucks or more i only paid 5 dollars for each cream just too 10 bucks in all! Cause of my insurance If you dont have its expensive! But ask your doctor about it!

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Struggling again, NY
Apr 25th, 2006
How well it works
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Affordability
:)

O.K... I didnt think I would be back on this site again but here I am with another dilemma. I had been using Differin for about 4 months and although it started out a little shaky, everything turned out O.K.... Now that I need a refill on my perscription my insurance claims they wont pay for it.. I have tried to get other people to visit their dermatologist and give me their perscriptions but with no luck.. for some reason Insurance companies are reluctant to pay for the product if the person is over 25... since when.. Now I have to suffer with this debilitating problem or risk ordering it over the net from some company in Austria that might not even be the real thing..... Any suggestions...

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2 of 2 visitors found the following comment helpful.
Anonymous
Apr 20th, 2006
How well it works
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I have been using this for about approx. 6 months now in conjunction with Doxycycline and it has done wonders for me. It has dramatically improved my severe acne and still continues to do so. For people it hasn't worked for, it's because everyone reacts to different medicines in a different way. Dan said that Benzoyl Peroxide really worked for him, but for me it made my acne more worse and aggrevated. A number of other factors contributed to my acne that I noticed such as chocolate made my whole face erupt with cysts and took over a month to settle and stress which took over a month to settle also. Overall differn has improved my acne and continues to do so.

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