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Differin Adapalene (0.1%) Gel
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Brand: Differin

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Differin Adapalene (0.1%) Gel


Active Ingredients:
Adapalene (0.1%).

Inactive Ingredients:
Carbomer 940, edetate disodium, methylparaben, poloxamer 182, propylene glycol, purified water and sodium hydroxide.

The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.

Differin Adapalene (0.1%) Gel

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Differin Adapalene (0.1%) Gel

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Reviewed on September 14, 2015

Ive been using this for about 3 months now as a last resort. Ive been to dermatologists and theyve plamed me off with this as i have seborrheic dermatitis as well as this patch of pigmented skin. I can honestly say that this product has done nothing, hasnt made it better and hasnt made it worse so its pretty pointless.

Ruined my Face
Reviewed on September 14, 2015

Ive always had acne, but it was never super bad. Shortly after my 21st birthday I started getting more acne than usual so I thought I should get some medication for it.

After using this for 11 weeks I can say this is the worst product I could have ever used or continued to use.

The "initial breakout" only got worse and worse and now my face is disgusting to look at. I have huge red puss filled acne all over both cheeks that does NOT improve at all. It covers every square inch of the skin on my cheeks and jaw line, in places ive NEVER had acne before. It's very painful and embarrassing. Ive never had such low self esteem or been so disgusted with my appearance.

Thanks to this gel I never go out anymore and when I see myself in the mirror I start to cry.

It says takes 8-12 weeks to work, but at week 11 I see no point in torturing myself anymore in hopes it might turn around, which it has shown no signs of doing. At this point I can only hope my face recovers with minimal scarring.

If you really hate someone, recommend them this product.

Fantastic stuff
Reviewed on September 3, 2015

Having done accutane TWICE and having acne re occur every time I seriously felt like there was no hope for my skin until I finally had the balls to start Differin after hearing all the horror storis. Yeah I had a bit of an initial breakout in hindsight. But the main word here is hindsight - I didn't even feel like I was having one as it really wasn't that bad. I am on my 9th week of treatment and will continue this forever. Since week 6 I have had only 4 or 5 tiny pimples that have disappeared quicker than they appeared! After a couple of weeks of flaking my skin really adjusted to it and it no longer makes me go red or flake at all. As long as this keeps working I will give it 5 stars!

Reviewed on August 21, 2015

before differin, I was using clean and clear (the wash and the moisturizer) and it cleared up my face. had a pimple and here and there but nothing to severe. during the summer, I really didn't keep up with the wash and one day, I looked in the mirror and my face was full of pimples on my forehead and cheeks. I went back to the wash and basically my forehead only cleared up. I was suppose to go to a dermatologist long time ago but I finally went.

the doctor prescribed me differin and told me peeling and burning may occur. and it sure did. the first night I used it, my face felt dry and tight. just smiling would hurt. in the morning I wash my face with clean and clear because I refuse to have dry skin all day. the second night I used differin, my skin burned so badly. I couldn't take it. dried it out and the peeling occurred. the worst part is school starts in just a few days. I wait about 20 minutes before applying moisturizer and it helps a bit.

I have peeling around my mouth, corner of my eyes and on my eyelids and I DONT apply it there but it's starting to die down. it's mostly just dry and flaky skin on the corner of mouth which I hope goes away within the next two days.

the third night was actually better. my face felt dry but nothing moisturizer can't fix. I'm going to keep updating hoping that things get better and I see some results within the next week or so.

Differin (Adapalene) Review
Reviewed on August 10, 2015

On this site it says it is used to treat 'severe' acne. This is incorrect as the leaflet clearly says used to treat 'mild to moderate acne'. I have seen some improvement. I am optimistic as this is day 5 for me. I have been combining with steaming my face about twice a week, prior to application every night . It works for me that way. I have had no adverse effects. Perhaps because I was using DUAC cream (5% benzoyl peroxide) prior to this to which my skin developed a tolerance, so was proving ineffective even though initially it was great. Hence the change. I would recommend this product as so far, I find it gentle and seems to be working.

Tried for almost 1 year
Reviewed on June 22, 2015

After using this religiously for almost an entire year (in combination with occasional use of 5% benzoyl peroxide) and doxycycline oral, I quit it and the doxycycline pill completely, as I saw improvements from a horrible break out after about 3 weeks when I first began... however, over time the improvements in my "monthly" flareup around my period were less significant and I found myself wondering if either medicine was doing anything to help at all anymore or if my hormones were the culprit for both making my skin less red and pimply or more. I would say this treatment isn't a long-term fix-all for acne, but works for an immediate fix - at least this is my experience!

by strongbad19 on 08/05/2015 03:05
You need to use this for more than 3 weeks. The acne bacteria lies deep in your skin and this, for lack of a better word, pulls it to the surface, kills it so that the true healing process may begin.
Works really Well!!
Reviewed on May 20, 2015

So i have used Differin for about 2 weeks and i already see A HUGE difference i had suffered 4 years with acne and THIS WORKS. IF you wear in the sunlight you are very likly to get sunburnt so put it on when you Go to bed make sure ITS right before you go to bed and make sure its a really thin layer.

Works AND no side effects!
Reviewed on April 27, 2015

I was prescribed Differin 0.1% gel, as well as being prescribed lymecycline tablets (1 a day).. Been on both prescriptions about 2/3 weeks and my skin has all cleared, literally only about 2 spots on my face!!!

Obviously I can't say which treatment is doing the magic but as a combination all I can say is AMAAAZING!!!

Really recommend it!

Also, I've read that some people experience irritation and itching with this gel but so far I've had no side effects!

by shupti on 08/28/2015 14:29
i am suffering from acne for 2 months and i dont have any major problm.. can i use this cream??
by shupti on 08/28/2015 14:30
i am suffering from acne for 2 months and i dont have any major problm.. can i use this cream??
Huge let down
Reviewed on April 21, 2015

I have been on Differin .03% for four months and 2 days and today I am experiencing one of the worst breakouts to date. I had seen improvement but nothing consistent. Looking at my face today, one would never guess I was taking care of my skin. My entire right side mouth/jaw/chin area has several inflamed pus filled acne that is hard to the touch. It looks disgusting. I choose not to wear makeup so everything is out there for the world to see. I usually go through a breakout and then a clear up cycle but I can't foresee this getting any better. The pros I suppose is that Differin is the gentlest retinoid of the lot and will last you forever. I recommend people give it 3-6 months before throwing in the towel just so that they can mark it off their list if it doesn't work. I am going to stick it out until the 6 month mark and will update if my review changes.

Hopefully this will not discourage anyone from trying this as different people react differently to different retinoids.

by strongbad19 on 08/05/2015 03:07
Did your doctor prescribe other medication to go with this? Mine gave me doxy for 2 months and then we began a regiment with Differin and Benzaclin (to kill the bacteria quickly).
Week 3
Reviewed on March 19, 2015

Hi everyone, I'm new to the forum but came across it last night in a fit of desperation about my skin! To give the context, I'm 29 and live in the UK. I don't have severe acne, but I suffer from large, very sore and inflamed papules around my jawline and mouth. I was prescribed Zineryt about 3 years and to begin with, it worked brilliantly. However it eventually stopped working, primarily because Zineryt is an antibiotic -based medicine, and I have become resistant to it, as many of you probably have if you've used it or something similar. After getting very fed up, I called my GP again and was prescribed Differin (over the phone, without actually seeing my face, I will add...). I'm on week 3, and although I haven't noticed any dramatic changes, it doesn't seem to be getting any worse, which is positive. I've got a few little bumps but none of the enlarged papules around my jaw line as before. My GP said it would take about 4-6 weeks to see a difference and to stick with it. I have a few things to say to give you all some advice which may give you all a little hope:

Firstly, don't be tempted to put on more than necessary - it won't get rid of the acne any quicker. For those who have experienced intense redness, itching, irritation, try using less product to see whether this will make a difference. If it doesn't help and you still have upset skin, go back to the GP/dermatologist. Perhaps it's just not suitable for your skin. I personally am allergic to Quinoderm and Duac, because of the actives in it. That's the main reason I was put on Differin and Zineryt, because of the strong reaction I have had to Benzoyl Peroxide products.

Second, for those worried about scarring. You need to let the acne heal before you can treat the scars. I have attended a couple of dermatology conferences due the nature of my job, and I have heard time and time again that the acne has to be treated and healed before the scarring can be tackled. There are many options out there but it's a question of waiting and being patient.

I'll give an update in a few weeks to see where I am with the Differin. Like you guys, I really hope it works too. To answer the question a lot of you are asking, it definitely makes the skin dry and flaky. It's mainly noticeable when applying make-up in the morning (I apply my Differin at night). The key here is moisturising and gentle exfoliating. This also applies to those with oily skin. Don't be tempted to skip the moisturiser because you have oily skin. You need to keep the skin lubricated so it won't over compensate and produce extra sebum.

Good luck, everyone.

by Zany*MJ on 09/20/2015 13:19
Differing=adaferin gel??????????